> Biospecimen Banking Program

The goal of the CPDR Biorepository is to support translational studies at CPDR, and complement efforts of other investigators in the field, by providing human biologic specimens unique to CPDR. Our current comprehensive bio-repository consists of paraffin-embedded whole-mounted prostate tissue specimens, OCT-embedded frozen tissue specimens, peripheral blood derived epithelial cell/DNA/RNA samples, a large serum bank, a Prostate Cell Center developing novel primary cell cultures, and a laser capture micro-dissection (LCM)-derived paired tumor and normal cell DNA/RNA bank.

Mission

The mission of the CPDR Biorepository is summarized in the following aims:

1. Collect, process and bank well characterized prostate tissue and blood-related biological samples, and provide these specimens, linked to clinical and pathological data, for translational prostate cancer research projects witihn and outside the CPDR.

2. Develop and provide cell-based experimental model systems to support translational research by complementing the tissue-based experimental systems derived from human prostate specimens.

Vision

The vision for the CPDR Biorepository is a solid integration of experimental data from tissue genomics, serum and tissue proteomics, and the Cell Center efforts, with the longitudinally-collected clinical and pathologic patient data, to create a comprehensive molecular relational database for extensive data-mining in close collaboration with the CPDR Tr-service National Database Program further strengthening research efforts in the CPDR.