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CPDR's ERG Antibody Leads to Successful Opportunities
February 14, 2011
The Center for Prostate Disease Research (CPDR) and the Uniformed Services University of the Health Sciences (USUHS) - with the Henry M. Jackson Foundation (HJF) for the Advancement in Military Medicine - are excited to announce a licensing agreement with Biocare Medical for the exclusive worldwide sales and distribution of the anti-ERG monoclonal antibody (ERG-MAb).
This antibody has potential to be used for in vitro diagnostics, prognostics, patient monitoring, and screening by immunohistochemistry. The CPDR-USUHS collaborative research endeavor also involves investigators from the Walter Reed Army Medical Center, the Armed Forces Institute of Pathology, and Biocare Medical to further study the ERG-MAb and its clinical diagnostic potential.
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2010 Internship Program Immerses Minority Students in Prostate Cancer Research
August 31, 2010
Five interns were selected for the 2010 program based on academic achievements at UDC in prostate cancer research. CPDR provided a structured framework for the program, offering a rich multi-disciplinary prostate cancer translational research environment that is credited for landmark discoveries. The students completed their program by presenting their training and research accomplishments at USU to leaders from the participating organizations. Dr. Taduru Sreenath, CPDR assistant director, served as the primary coordinator for the program...
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ERG Oncoprotein
Scientists develop highly specific ERG monoclonal antibody for detecting common oncogenic alterations in prostate cancer.
June 29, 2010
Bethesda, Maryland--Researchers at the Uniformed Services University of the Health Sciences (USU) Center for Prostate Disease Research (CPDR), in collaboration with investigators at the Armed Forces Institute of Pathology and Walter Reed Army Medical Center have developed a highly specific assay for the detection of ERG oncoprotein that is regulated by prevalent gene fusions present in over half of all prostate cancers. These findings are reported in the advanced online publication of Prostate Cancer and Prostatic Diseases (Nature Publishing Group, June 29), “ERG oncoprotein expression in prostate cancer: clonal progression of ERG-positive tumor cells and potential for ERG-based stratification.”
PCAN Journal Article
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AUA 2010 Highlights
CPDR presentations and highlights at the American Urologic Association Annual Meeting San Francisco, May 30-June 3, 2010:
June 11, 2010
The multi-disciplinary team of Center for Prostate Disease Research led by COL (ret) David McLeod, MD, CPDR Director and Professor at Uniformed Services University and Dr. Shiv Srivastava, PhD, Co-Director and Professor at Uniformed Services University presented five abstracts in moderated poster sections of the American Urologic Association Annual Meeting ...
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AACR 2010 Highlights
AACR 101st Annual Meeting Presentations from CPDR
Washington DC, April 17 – 21, 2010
June 10, 2010
More than 18,000 participants from countries gathered to discuss an estimated 5,500 abstracts and to hear several hundreds of symposium presentations on significant discoveries in basic, clinical, and translational cancer research at the 101th Annual Meeting of the American Association of Cancer Research, in Washington DC. ...
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Summer Internship Program Immerses Minority Students in Prostate Cancer Research
November 9, 2009
The Uniformed Services University of the Health Sciences (USU) Center for Prostate Disease Research (CPDR) played host recently to seven students from the University of the District of Columbia for a rigorous twelve-week training internship focused on prostate cancer research.
The internship was established jointly by the CPDR, which is part of USU’s Department of Surgery, and the University of the District of Columbia (UDC) in 2008 ...
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September is Prostate Cancer Awareness Month
September 1, 2009
Date: Saturday 26 September
Time: 0700-1100
Location: Walter Reed Army Medical Center, 5th Floor, CPDR Ward 56
Help us spread the word to your friends and colleagues (who
are military beneficiaries) so they can be checked for prostate cancer.
Early detection is the key!
Please download and forward the flyer linked below (pdf format) to your friends and colleagues who are military health care beneficiaries -- or post it on bulletin boards at work if retired/active duty military employees. Help spread the word by doing what you can to encourage or persuade your male buddies to get smart about their PSA readings. You know how important this is--- more than anybody! A nudge from a buddy may be all that is needed!
Prostate Screening Flyer
Prostate Cancer on CNN Larry King Live!
August 21, 2009
Colin Powell, tennis champ John McEnroe and L.A. Dodger’s manager Joe Torre come together to save lives! They speak out on one of the deadliest cancers for men! Powell, McEnroe and Torre on surviving and preventing prostate cancer!
See Video Footage - 8/21/2009
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CPDR Takes Five Awards
February 2, 2009
The 56th James C. Kimbrough Urological Seminar brought great recognitions to CPDR. This year the seminar was held in Washington DC.
COL (Ret.) David G.McLeod was honored with the H. G. Stevenson award. In 1992 the Society of Government Service Urologists established this award, which is presented annually for outstanding support and dedicated service to the Society. The recipient of this award can be a Corporate Member, physician, or other individual as determined by the Board of Directors.
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CPDR Director, Dr. David G. McLeod, is Guest Blogger on WebMD
October 20, 2008
CPDR Director, Dr. David G. McLeod, posted an article titled, “Prostate Cancer: Know the Risk Factors,” to WebMD’s blog site, in collaboration with Dr. Ward Casscells, the Assistant Secretary of Defense of Health Affairs (ASD-HA). The blog post presents a look at the risk factors of Prostate Cancer and highlights the Center for Prostate Disease Research, under the leadership of Dr. McLeod.
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USU’s Center for Prostate Disease Research Provides New Insights Into Common Alterations of ERG
Oncogene in Prostate Cancer
Monday, October 6, 2008
BETHESDA, Md. — In the past three years, ground-breaking discoveries in the prostate cancer field have highlighted that alterations of ETS related genes (predominantly ERG), as a result of a fusion between male hormone receptor regulated gene promoters (predominantly TMPRSS2) and ETS transcription factors, represent one of the most common oncogenic defects in prostate cancer. Researchers at the Center for Prostate Disease Research (CPDR) at the Uniformed Services University of the Health Sciences (USU) had originally shown frequent overexpression (60-70%) of the ETS related gene ERG in the epithelial cell transcriptome of prostate cancers. In their continued quest to understand the functional role and clinical utility of ERG alterations in prostate cancer, CPDR researchers have now defined new features of ERG function and expression which will further enhance the potential of ERG as promising biomarker and therapeutic target for prostate cancer.
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USU’s Center for Prostate Disease Research Reports New Prognostic Utility of PCA3 Molecular Urine Test
Monday, October 6, 2008
BETHESDA, Md. — In a recent report, the collaborative research team from the Center for Prostate Disease Research at the Uniformed Services Universit of the Health Sciences (USU) and Walter Reed Army Medical Center (WRAMC) and Gen-Probe Inc., San Diego, Calif., showed a new promising prognostic utility of the urine PCA3 test.
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