biospecimen banks

CPDR Biospecimen Banks

New Challenges in Predicting the Clinical Course for CaP Patients

It is worth noting that well-characterized biospecimens from our group and others have already contributed immensely to the novel molecular discoveries made in the field of CaP research. Therefore, with a proven track record, the continued development and enhancement of the CPDR Biospecimen Bank holds great promise for much needed translational research at CPDR and at other institutions through collaborative research agreements.

The biospecimen storage and processing facilities that comprise the CPDR Biospecimen Bank are housed in four locations: the Walter Reed National Military Medical Center (WRNNMC) in Bethesda, MD; the headquarters of the Center for Prostate Disease Research (CPDR) in Rockville, MD; the Joint Pathology Center (JPC) in Washington, DC, and the Prostate Cell Center at the Department of Surgery of the Uniformed Services University (USU) in Bethesda, MD. These facilities have been processing biospecimens since 1993 and have a significant endowment of biospecimen resources. The biospecimen resources and analytical and processing services provided by these facilities have supported numerous studies conducted at the CPDR. These studies have resulted in over 60 peer-reviewed publications, 10 grants or CRADA, and five patents to date.

OBJECTIVES

  • Radical Prostatectomy Specimen Processing for Frozen Tissue Bank Generation
  • Histological Characterization
  • Radical Prostatectomy Specimen Processing for Fixed, Paraffin-embedded Tissue Bank Generation
  • Laser Capture Microdissection (LCM) of Prostate Tissues and Generation of
    LCM/RNA and Genomic DNA Bank
  • Development of Tissue Microarrays (TMA)
  • Peripheral Blood Collection and Processing to Generate Serum and genomic DNA Banks
  • Serum Preparation
  • Peripheral Blood DNA Bank

More recently, active collaborations have been sought by corporate partners and academic leaders to use CPDR Bio-specimens bank. A Biospecimen Oversight Committee and Research Opportunity Evaluation Committee have been instituted recently to monitor the prioritization of bio-specimens for in-house use and collaborations.

 

CURRENT EVENTS


WRNMMC UsToo!
Quarterly Guest Speakers


Dr. Albert Dobi

Associate Director, CPDR Basic Science Research Program
Research Assistant Professor of Surgery, USUHS

Dr. DobiPresentation: "Recent Advancements in Prostate Cancer Detection, Prognosis, and Therapy"

Date: 7 Aug 2014
Time: 7-8:30 PM
Location: WRNMMC, America Building, 2nd floor, Room 2525
Contact: COL (ret) Jane Hudak for more information
at 301-319-2918 or jane.l.hudak.ctr@health.mil

Read the AUGUST 2014 Newsletter

 

CURRENT PUBLICATIONS



Expression of ERG Oncoprotein in Higher Grade Prostate Cancer in Caucasian American and African American Men
Farrell J, Young D, Chen Y, Degon M, Cullen J, Petrovics G, Rosner I, Kagan J, Srivastava S, McLeod DG, Sesterhenn IA and Srivastava S.
Molecular and Clinical Oncology 2014 (in press).

ERG Oncoprotein Expression Status In A Multi-Ethnic Cohort Of Cap Patients From Malaysia
Kelly GM, Kong YH, Tan S-H, Dobi A, Sesterhenn IA, Srivastava S, Pathmanathan R, Tan HM, Cheong SC.
Molecular and Clinical Oncology, 2014 (in press).

Legends in Urology: Fathollah Keshvar "Kash" Mostofi, MD. An Interview with Isabell Sesterhenn, MD
Haas G.
Canadian Journal of Urology (21) 3 Jun 2014.