CPDR Biospecimen Banks
New Challenges in Predicting the Clinical Course for CaP Patients
It is worth noting that well-characterized biospecimens from our group and others have already contributed immensely to the novel molecular discoveries made in the field of CaP research. Therefore, with a proven track record, the continued development and enhancement of the CPDR Biospecimen Bank holds great promise for much needed translational research at CPDR and at other institutions through collaborative research agreements.
The biospecimen storage and processing facilities that comprise the CPDR Biospecimen Bank are housed in four locations: the Walter Reed National Military Medical Center (WRNNMC) in Bethesda, MD; the headquarters of the Center for Prostate Disease Research (CPDR) in Rockville, MD; the Joint Pathology Center (JPC) in Washington, DC, and the Prostate Cell Center at the Department of Surgery of the Uniformed Services University (USU) in Bethesda, MD. These facilities have been processing biospecimens since 1993 and have a significant endowment of biospecimen resources. The biospecimen resources and analytical and processing services provided by these facilities have supported numerous studies conducted at the CPDR. These studies have resulted in over 60 peer-reviewed publications, 10 grants or CRADA, and five patents to date.
- Radical Prostatectomy Specimen Processing for Frozen Tissue Bank Generation
- Histological Characterization
- Radical Prostatectomy Specimen Processing for Fixed, Paraffin-embedded Tissue Bank Generation
- Laser Capture Microdissection (LCM) of Prostate Tissues and Generation of
LCM/RNA and Genomic DNA Bank
- Development of Tissue Microarrays (TMA)
- Peripheral Blood Collection and Processing to Generate Serum and genomic DNA Banks
- Serum Preparation
- Peripheral Blood DNA Bank
More recently, active collaborations have been sought by corporate partners and academic leaders to use CPDR Bio-specimens bank. A Biospecimen Oversight Committee and Research Opportunity Evaluation Committee have been instituted recently to monitor the prioritization of bio-specimens for in-house use and collaborations.
CPDR WEEKLY SEMINAR
Alagarsamy Srinivasan, PhD
Assistant Director, BSRP
Presentation: "Liquid Biopsy in Prostate Cancer"
Date: April 28, 2017
Time: 11:00 am -12:00 pm
Location: CPDR, Rockville, MD
2nd floor conference room
Guest Speaker Program
Dr. Robert Dean
Director of Andrology
Walter Reed National Military Medical Center
Presentation: “Prostate Cancer Survivorship: Sexual Health Therapies”
Date: Thursday 4 May 2017
Location: Walter Reed National Military Medical Center (America Building, 2nd floor, Room 2525) and Fort Belvoir Community Hospital (via video teleconference in Oaks Pavilion, 1st floor, Room 332).
A military ID card is required to get on base at Walter Reed. Attendees without a military ID need to call the Prostate Center at 301-319-2900 at least 4 business days in advance to complete paperwork for gate access approval. Also bring some form of picture identification at the gate.
Read the May 2017 WRNMMC UsToo! Newsletter
Read the April 2017 CPDR E-Newsletter
April 7, 2017
Highlights at the 2017 AACR Annual Meeting in Washington, D.C.
The Center for Prostate Disease Research (CPDR) multi-disciplinary team - together with collaborators - presented 8 abstracts in moderated poster presentations at the American Association of Cancer Researchers Annual Meeting, April 1-5, 2016, Wasahington, DC. The team was co-led by Dr. Shiv Srivastava, CPDR Co-Director and Professor in the Department of Surgery at USU and WRNMMC and Dr. Albert Dobi, Associate Director, CPDR and Research Assistant Professor, Department of Surgery , USU and WRNMMC.
Autoantibodies against oncogenic ERG protein in prostate cancer: potential use in diagnosis and prognosis in a panel with C-MYC, AMACR and HERV-K Gag
Genes Cancer. 2016 Nov;7(11-12):394-413. doi: 10.18632/genesandcancer.126.
Re: Inherited DNA-repair Gene Mutations in Men with Metastatic Prostate Cancer
Eur Urol. 2017 Jan 5. pii: S0302-2838(16)30922-8. doi: 10.1016/j.eururo.2016.12.018. [Epub ahead of print]